Why ZEMBRACE SymTouch?

Migraine attacks can vary

Are your attacks always the same?

There’s more to migraine than just the headache. The speed that an attack comes on can change, and so can the severity of the symptoms a person experiences during a migraine. People with migraines can suffer from more than just headache pain—sufferers may also experience 1 or more of the following during each attack:

When it comes to your migraines:

You are not alone. In 2 self-reported surveys of 500 and 29,727 patients, more than 73% of migraine patients suffer from nausea or vomiting.

There's more you can do

Does your medication address every attack?

Migraine sufferers know: One size does not fit all attacks. It's important to weigh your treatment options against your symptoms so you can be prepared for your next migraine. Ask yourself...

  • Would you like relief in as little as 10 minutes?
  • Do you ever wait to take your oral medication because you are nauseous?
  • Do you ever feel like you can't "catch up" when a migraine comes on fast?

If you answered yes to any of the above, ZEMBRACE SymTouch may be right for you.

Based on the variability of your migraine attacks, your doctor can help identify the right treatment plan for you.

ZEMBRACE SymTouch benefits

Get the facts

Fast.

17% of people started feeling pain relief in as little as 10 minutes (compared with 5% for placebo).

Powerful
relief.

60% of patients experienced pain relief
2 hours after administration.

Ready.

A prefilled, 2-step treatment pen that goes with you and requires no refrigeration.*

Flexible.

The recommended dose is 3 mg, which may be taken up to 4 times a day (12 mg) with at least
1 hour between doses.

ZEMBRACE SymTouch is a subcutaneous injection used to treat migraine headaches with or without aura in adults, 18 years or older, who have been diagnosed with migraine.

Simple

Relief that goes with you

ZEMBRACE SymTouch can provide you with fast relief in a simple, two-step injection process:

Two Step
Watch our Instructions for Use video to see for yourself just how easy it is to use.
video Placeholder
A prefilled, ready-to-use, single-dose, 3 mg sumatriptan pen, ZEMBRACE SymTouch can be carried almost anywhere and used anytime you may need fast migraine relief. And it requires no refrigeration!*

*Store between 20°C and 25°C (68°F and 77°F). Excursions permitted between 15°C and 30°C (59°F and 86°F). NOTE: Do not refrigerate ZEMBRACE SymTouch.

As with all injection medications, be sure that the injection site is properly cleaned, and that the used ZEMBRACE SymTouch pen is properly disposed of immediately after use. Please see complete Instructions For Use for more information.

IMPORTANT SAFETY INFORMATION

What important information should I know about ZEMBRACE SymTouch?

ZEMBRACE SymTouch can cause serious side effects, including: heart attack and other heart problems, which may lead to death. Stop using ZEMBRACE SymTouch and get emergency medical help right away if you have any of the following symptoms of a heart attack:

  • chest pain or chest discomfort that feels like an uncomfortable heavy pressure, tightness or heaviness, or pain that lasts for more than a few minutes, or that goes away and comes back
  • pain or discomfort in your arms, back, neck, jaw, or stomach
  • shortness of breath
  • breaking out in a cold sweat
  • nausea or vomiting
  • feeling lightheaded

ZEMBRACE SymTouch is not for people with risk factors for heart disease (high blood pressure, high cholesterol levels, smoking, overweight, diabetes, family history of heart disease) unless a heart exam is done and shows no problem.

Who should not use ZEMBRACE SymTouch?

Do not use ZEMBRACE SymTouch if you have:
  • heart problems or a history of heart problems
  • had a stroke, transient ischemic attacks (TIAs), or problems with your blood circulation
  • narrowing of blood vessels to your legs or arms (peripheral vascular disease), stomach, or kidney
  • uncontrolled high blood pressure
  • hemiplegic migraines (that make you unable to move on one side of your body) or basilar (rare form of migraine with aura) migraines. If you are not sure if you have these, ask your healthcare provider
  • taken any of the following medicines in the last 24 hours: sumatriptan, almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, sumatriptan and naproxen, ergotamines, or dihydroergotamine. Ask your healthcare provider if you are not sure if your medicine is listed above
  • severe liver problems
  • an allergy to sumatriptan or any of the components in ZEMBRACE SymTouch

What should I tell my healthcare provider before taking ZEMBRACE SymTouch?

Tell your healthcare provider about all of your medical conditions, and about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

What should I avoid while using ZEMBRACE SymTouch?

ZEMBRACE SymTouch can cause dizziness, weakness, or drowsiness. If you have these symptoms, do not drive a car, use machinery, or do anything where you need to be alert.

What are possible side effects of ZEMBRACE SymTouch?

ZEMBRACE SymTouch may cause serious side effects including:
  • changes in color or sensation in your fingers and toes (Raynaud’s syndrome)
  • stomach and intestinal problems (gastrointestinal and colonic ischemic events)
  • problems with blood circulation to your legs and feet (peripheral vascular ischemia)
  • hives (itchy bumps); swelling of your tongue, mouth, or throat
  • medication overuse headaches. Some people who use too many ZEMBRACE SymTouch injections may have worse headaches (medication overuse headache)
  • serotonin syndrome. Serotonin syndrome is a rare but serious problem that can happen in people using ZEMBRACE SymTouch, especially if used with antidepressant medicines
    • Call your healthcare provider right away if you have any of the following: symptoms of serotonin syndrome: mental changes such as seeing things that are not there (hallucinations), agitation, or coma; fast heartbeat; changes in blood pressure; high body temperature; tight muscles; trouble walking; or nausea, vomiting, or diarrhea
  • serious allergic reactions. Get medical help right away if you have any of these symptoms of a serious allergic reaction: swelling of your face, lips, mouth, or tongue; trouble breathing; wheezing; severe itching; skin rash, redness, or swelling; dizziness or fainting; fast heartbeat or pounding in your chest; or sweating
  • Seizures have happened in people taking sumatriptan who have never had seizures before

The most common side effects of ZEMBRACE SymTouch include pain and redness at your injection site; tingling or numbness in your fingers or toes; dizziness; warm hot burning feeling to your face (flushing); discomfort or stiffness in your neck; feeling weak, drowsy, or tired.

These are not all the possible side effects of ZEMBRACE SymTouch. For more information, ask your healthcare provider or pharmacist. You are encouraged to report negative side effects of prescription drugs. To report SUSPECTED SIDE EFFECTS, call Promius Pharma at 1-888-966-8766 or contact the FDA at 1-800-FDA-1088 (1-800-332-1088) or online at http://www.fda.gov/Safety/MedWatch

INDICATION AND USAGE

What is ZEMBRACE SymTouch used for?

ZEMBRACE SymTouch is a prescription medicine used to treat acute migraine headaches with or without aura in adults who have been diagnosed with migraine.

ZEMBRACE SymTouch is not used to prevent or decrease the number of migraines you have. It is not known if ZEMBRACE SymTouch is safe and effective in children under 18 years of age.


Please see Patient Information, Instructions For Use and Full Prescribing Information for ZEMBRACE SymTouch.

IMPORTANT SAFETY INFORMATION

What important information should I know about ZEMBRACE SymTouch?

ZEMBRACE SymTouch can cause serious side effects, including: heart attack and other heart problems, which may lead to death. Stop using ZEMBRACE SymTouch and get emergency medical help right away if you have any of the following symptoms of a heart attack:

  • chest pain or chest discomfort that feels like an uncomfortable heavy pressure, tightness or heaviness, or pain that lasts for more than a few minutes, or that goes away and comes back
  • pain or discomfort in your arms, back, neck, jaw, or stomach
  • shortness of breath
  • breaking out in a cold sweat
  • nausea or vomiting
  • feeling lightheaded

ZEMBRACE SymTouch is not for people with risk factors for heart disease (high blood pressure, high cholesterol levels, smoking, overweight, diabetes, family history of heart disease) unless a heart exam is done and shows no problem.

Who should not use ZEMBRACE SymTouch?
Do not use ZEMBRACE SymTouch if you have:
  • heart problems or a history of heart problems
  • had a stroke, transient ischemic attacks (TIAs), or problems with your blood circulation
  • narrowing of blood vessels to your legs or arms (peripheral vascular disease), stomach, or kidney
  • uncontrolled high blood pressure
  • hemiplegic migraines (that make you unable to move on one side of your body) or basilar (rare form of migraine with aura) migraines. If you are not sure if you have these, ask your healthcare provider
  • taken any of the following medicines in the last 24 hours: sumatriptan, almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, sumatriptan and naproxen, ergotamines, or dihydroergotamine. Ask your healthcare provider if you are not sure if your medicine is listed above
  • severe liver problems
  • an allergy to sumatriptan or any of the components in ZEMBRACE SymTouch
What should I tell my healthcare provider before taking ZEMBRACE SymTouch?

Tell your healthcare provider about all of your medical conditions, and about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

What should I avoid while using ZEMBRACE SymTouch?

ZEMBRACE SymTouch can cause dizziness, weakness, or drowsiness. If you have these symptoms, do not drive a car, use machinery, or do anything where you need to be alert.

What are possible side effects of ZEMBRACE SymTouch?
ZEMBRACE SymTouch may cause serious side effects including:
  • changes in color or sensation in your fingers and toes (Raynaud’s syndrome)
  • stomach and intestinal problems (gastrointestinal and colonic ischemic events)
  • problems with blood circulation to your legs and feet (peripheral vascular ischemia)
  • hives (itchy bumps); swelling of your tongue, mouth, or throat
  • medication overuse headaches. Some people who use too many ZEMBRACE SymTouch injections may have worse headaches (medication overuse headache)
  • serotonin syndrome. Serotonin syndrome is a rare but serious problem that can happen in people using ZEMBRACE SymTouch, especially if used with antidepressant medicines
    • Call your healthcare provider right away if you have any of the following: symptoms of serotonin syndrome: mental changes such as seeing things that are not there (hallucinations), agitation, or coma; fast heartbeat; changes in blood pressure; high body temperature; tight muscles; trouble walking; or nausea, vomiting, or diarrhea
  • serious allergic reactions. Get medical help right away if you have any of these symptoms of a serious allergic reaction: swelling of your face, lips, mouth, or tongue; trouble breathing; wheezing; severe itching; skin rash, redness, or swelling; dizziness or fainting; fast heartbeat or pounding in your chest; or sweating
  • Seizures have happened in people taking sumatriptan who have never had seizures before

The most common side effects of ZEMBRACE SymTouch include pain and redness at your injection site; tingling or numbness in your fingers or toes; dizziness; warm hot burning feeling to your face (flushing); discomfort or stiffness in your neck; feeling weak, drowsy, or tired.

These are not all the possible side effects of ZEMBRACE SymTouch. For more information, ask your healthcare provider or pharmacist. You are encouraged to report negative side effects of prescription drugs. To report SUSPECTED SIDE EFFECTS, call Promius Pharma at 1-888-966-8766 or contact the FDA at 1-800-FDA-1088 (1-800-332-1088) or online at http://www.fda.gov/Safety/MedWatch

Please see Patient Information, Instructions For Use and Full Prescribing Information for ZEMBRACE SymTouch or visit www.zembrace.com.

INDICATION AND USAGE

What is ZEMBRACE SymTouch used for?

ZEMBRACE SymTouch is a prescription medicine used to treat acute migraine headaches with or without aura in adults who have been diagnosed with migraine.

ZEMBRACE SymTouch is not used to prevent or decrease the number of migraines you have. It is not known if ZEMBRACE SymTouch is safe and effective in children under 18 years of age.