What is Zembrace® SymTouch®

A ready-to-use, single-use, 3 mg sumatriptan pen (auto-injector).

a thin/small hidden needle, compact design, a simple two step injection process 1,2

No two migraines are the same

Different migraines require different approaches. Migraine is a debilitating disease that can be further complicated when certain symptoms are present.

How can Zembrace® SymTouch® help?

Zembrace® SymTouch® is indicated for the acute treatment of migraine with or without aura in adults.

If you suffer from any of the following migraines, Zembrace® SymTouch® may be able to help:


Nearly half of all migraine attacks occur between 4 and 9 a.m.3


A migraine that reaches full force quickly.

with nausea

73% of patients with migraine have experienced nausea (with or without vomiting) during migraine attacks.4

Do not use Zembrace® SymTouch® if you have: heart problems or a history of heart problems; had a stroke, transient ischemic attacks (TIAs), or problems with your blood circulation. These are not all of the reasons you should not use Zembrace® SymTouch®. See the Important Safety Information, and speak with your healthcare provider for more information about whether Zembrace® SymTouch® is right for you.


  1. Brand-Schieber E, Munjal S, Kumar R, et al. Human factors validation study of 3 mg sumatriptan autoinjector, for migraine patients. Med Devices (Auckl). 2016;9:131-137.
  2. Zembrace SymTouch [package insert]. Maple Grove, MN: Upsher-Smith Laboratories, LLC: February 2021.
  3. Top 10 migraine triggers and how to deal with them. American Migraine Foundation. https://americanmigrainefoundation.org/resource-library/top-10-migraine-triggers-and-how-to-deal-with-them/. Published July 27, 2017. Accessed 2021.
  4. Newman LC. Why triptan treatment can fail: focus on gastrointestinal manifestations of migraine. Headache. 2013;53 Suppl 1:11-16.